What is the first-line therapy for osteoarthritis and the mechanism of action?

Sally is a 50-year-old female who has been a jogger for several years. She has recently been diagnosed with osteoarthritis. She has been taking ibuprofen for 3 months but states that “it does not help” and hurts her stomach. The health care provider prescribes celecoxib (Celebrex) 100 mg orally twice a day.What is the first-line therapy for osteoarthritis and the mechanism of action?Sally expresses concern about all the recent news about heart problems and celecoxib (Celebrex). What information should be included in a teaching plan to help her understand about taking celecoxib and the benefits and risks?Ibuprofen and celecoxib are both nonsteroidal anti-inflammatory drugs. Explain how they are similar and different.Submission Instructions:APA 7 edition is a must.NO WEBSITES ALLOWED FOR REFERENCE OR CITATION. 500 words at least. References and citation must be only from journal articles or books published from 2017 up to now. Must employ at least 3 references entries which will be cited at the end of the paragraph. INCLUDE DOI, PAGE NUMBERS. etc PLAGIARISM NEED TO BE LESS THAN 10%.

Create a security plan for a medium sized health care facility.

Create a security plan for a medium sized health care facility. In your security plan, evaluate how you would approach security threats from both inside and outside the organization. Be sure that you address the following items in your security plan:physical and administrative safeguards: employee education, health information archival and retrieval systems, disaster recovery, storage mediaaccess safeguards: authentication, password managementnetwork safeguards: cloud computing, firewalls, encryption / decryption and using mobile devices to deliver healthcareCritique the plan you have written, identifying its strengths, elements that were not covered in the text, and any additional omissions or weaknesses of the plan.As a reference, you may want to visit the following website:Source: HIPAA Privacy, Security, and Breach Notification Audit Program: United States Department of Health & Human Services. Retrieved from http://www.hhs.gov/ocr/privacy/hipaa/enforcement/audit/index.htmlRequirements:The Assignment should be 2–3 pages in length, prepared in a Microsoft Word document, and APA-formatted.Include a title page and reference page. Length requirements do not include the title page, and the reference page.Follow APA style format and citation guidelines, including Times New Roman 12 point font and double spacing.This Assignment should follow the conventions of Standard English featuring correct grammar, punctuation, style, and mechanics.Include at least two references. The course textbook counts as one reference. All sources must be scholarly. Wikipedia is not acceptable. Use APA style for all citations including course materials.Your writing should be well ordered, logical, and unified, as well as original and insightful.

Analyze at least two current events involving the agency that might have implications for personnel management

Scenario for AssignmentsPlease note, the assignments in this course build upon one another.For these assignments, you will take on the role of a consultant for a government agency. Your consulting firm has been asked by the agency to conduct background research, interview agency representatives, compile a report, and provide recommendations for improvement of their personnel management system. The first role of the consultant is to become familiar with the agency, its departments, and key actors. You will develop the assignment in four parts, submitting each to your supervisor (your professor) who will review and grade your efforts.Selecting an AgencyThe agency you select in this first assignment must be used for all remaining assignments. Before selecting your agency, review the directions for each of the assignments to ensure that your selected agency will address the requirements for each of the assignments.Explore one federal, state, or local government organization, and then select a department within that agency. Usually, you can find contact information on their website. You may want to consider these government websites.**PLEASE USE THE AGENCY: DEPARTMENT OF HOMELAND SECURITY**InstructionsSelect a federal or state public agency.Research the literature regarding issues that involve the selected agency and public administration in general.Interview one representative of the agency’s department for the different sections of the paper. (Interviews can be conducted in person, by phone, or by an electronic method such as email or your favorite video conferencing app.) See Guidelines for Interview Assignment at Strayer University (below).Write a 3–4 page paper, titled “Rationale and Analysis for Agency Selected.” Complete the following:Provide background information about the agency’s key historical events, mission, and goals/objectives (title this section “Introduction”).Describe at least three functions of this agency, highlighting the public it serves (title this section “Agency Functions”).Analyze at least two current events involving the agency that might have implications for personnel management (title this section “Agency News”).Explain your rationale for selecting this agency with at least two justifiable reasons (title this section “Rationale for Selecting Agency”).Appropriately incorporate at least four quality sources. A quality source can be either popular, such as a news article, or scholarly, such as peer-reviewed works. In the case of public administration, government websites are appropriate quality resources. Note: Wikipedia, SparkNotes, and similar websites do not qualify as academic resources

Should drug use be decriminalized? Explain

TOPIC: Should drug use be decriminalized? Explain Upon choosing this topic, you will submit a 3 page essay in APA format on this topic.The 3 pages do not count the cover page or referencesThe textbook and all outside references must be cited and referenced. This link will provide help on citations and references: https://apastyle.apa.org/style-grammar-guidelines/citations/basic-principles/author-date You will be graded on content, format, clarity, grammar and spelling. Each topic must use a minimum of two (2) academic articles which you can find on http://scholar.google.com and your textbook, for a total of three (3) references minimum.

Assuming cyber, WMD, and small boats pose threat #1, #2, and #3, what would be maritime threat number 4?

Assuming cyber, WMD, and small boats pose threat #1, #2, and #3, what would be maritime threat number 4? Why did you pick this one and what can the on-going public-private security regime do to address it? This of this from an asymmetric perspective. The post needs to be at least 400 words in APA format. Please use the link below for resources/sources and refer to Week 8. https://myclassroom.apus.edu/d2l/le/enhancedSequenceViewer/30473?url=https%3A%2F%2Ff54cbe36-23a9-4505-85fe-e251f80ec34d.sequences.api.brightspace.com%2F30473%2Factivity%2F2968992%3FfilterOnDatesAndDepth%3D1

Provide a bar graph showing three years of data on the most significant change

A minimum of three outside resources, write a 3-page paper detailing and analyzing the changes in households and how today’s marketing agents can use this information to develop their marketing strategies.RequirementsProvide a bar graph showing three years of data on the most significant changeThree (3) peer-reviewed journal articlesDemonstrate the importance of a change in Household Trends

Respond to the Warden on how you would proceed to correct one of the following conditions:

Assignment DetailsThe Governor is concerned with the number of inmates who are being victimized by assaults, including sexual assaults and stabbings and beatings. You have recently been assigned to a state penitentiary to interview inmates who have been victimized and to determine why there is such an alarming increase in these assaults. You are tasked with evaluating the conditions of the penitentiary and the effectiveness of the corrections officer force, along with the conditions in which the inmates are living.The Warden is also concerned and has asked you for any conditions that you may feel require correction. The Governor has promised appropriate budget increases to correct these issues.Respond to the Warden on how you would proceed to correct one of the following conditions:Residential overcrowdingEntire population attending meals at the same timeExcessive aggression by the corrections staffAll-inclusive yard time for the inmates when the entire population is togetherHandmade weapons being used in the assaultsLocations in work areas that cannot be observed or supervisedNo counselling for victims of the assaultsWeak responses to investigating the suspected offendersIn your replies to others, evaluate the proposed solutions for viability.

Describe some of the conflicting social, economic, and environmental costs, benefits, and issues associated with construction of the Three Gorges Dam.

Assignment 3: Stakeholders in Sustainable Business TransformationIntroductionIn this module, we explored a number of broad forces that have significant influence on business, government, and society. In this assignment, you will focus on environmental issues and sustainable development as a growing force in business and society today. Decision makers integrating environmental and social issues and concerns with economic goals can face conflicting costs and benefits among these three elements of sustainable development.In this assignment, you will examine some of the environmental and social costs and benefits associated with an economic development project. You will also examine one business or organization that is implementing sustainable development policies and initiatives.This assignment will comprise 15% of your total course mark. Part A is a case study on the environmental, social, and economic impacts of a new dam in China. Part B is a report examining a corporation or other organization that is transforming to more sustainable operations. Each question carries the marks as stated for a total of 100 marks.Part A: InstructionsRead the Discussion Case: “The Three Gorges Dam” on page 241 of Chapter 10 of your Business and Society textbook, and answer the following two questions. You should demonstrate your ability to incorporate and integrate your learning from all aspects of this module. Ensure that you include information from the course material, the readings, your journal, and your own research.Question 1: Describe some of the conflicting social, economic, and environmental costs, benefits, and issues associated with construction of the Three Gorges Dam. Remember to consider global as well as local and regional issues and impacts (or potential future impacts) of construction and operation of this dam. (25 Marks)Question 2: Describe the biases, perspectives, or experiences that may influence your views on the various costs and benefits of the Three Gorges Dam project. (5 marks)Part B: InstructionsIn Part B of this assignment, you examine a corporation or other organization that is transforming to more sustainable operations. In a 2500-word double-spaced report, analyze ways the organization is reacting to stakeholder influences and how the policies and initiatives of this organization, as well as technologies that they employ, are affecting stakeholders internally, externally, and globally. You should demonstrate your ability to incorporate and integrate your learning from all aspects of this module. Ensure that you include information from the course material, the readings, your journal, and your own research.You may choose from the following options:Royal Dutch Shell. Search Shell’s corporate website for “sustainable development” or “responsible energy” for reports and discussions about the company’s progress toward cleaner, more efficient energy production and other environmental initiativesInterface, Inc.. Information sources include the Interface corporate website at http://www.interfaceinc.com, and a discussion of Interface’s programs and progress athttp://www.interfacesustainability.com/Hewlett-Packard (HP). This organization refers to its commitment toward sustainability as its “corporate citizenship”: http://www.hp.com/hpinfo/globalcitizenship/index.htmlA business or organization of your choice that is implementing sustainable development policies and initiatives. Please review the questions below to ensure the organization or business that you select is appropriate to the assignment deliverables.Note: Prior to beginning this report (if you are not analyzing Shell, Interface, or HP), you should discuss with your Open Learning faculty member your chosen organization if you have any concerns as to whether the organization is appropriate.After selecting an organization, write a 2500-word double-spaced report containing the following:Section 1. External forces or influences: Identify three external factors that you think have influenced the company’s shift to more environmentally and/or socially responsible business management practices. Describe the ways in which these external factors influenced management actions and/or decisions or helped to transform the company. Provide evidence to support your observations. (30 marks)Section 2. Internal forces or influences: Identify two internal factors that have influenced the company’s shift to more environmentally and/or socially responsible business management practices. Describe the ways in which these internal factors influenced management actions and/or decisions or helped to transform the company. Provide evidence to support your observations. (20 marks)Section 3. Global impacts of sustainable development initiatives: Describe one real or potential global impact of the sustainable development initiatives of this company. Indicate the magnitude or significance of this impact in terms of its influence on global business and/or society. (10 marks)Section 4. Harnessing technology for sustainable development: Describe (with examples) how this company is using the Internet and other technologies to assist its efforts to move toward sustainable business and development. (10 marks)

Discuss the ways that virtue ethics is in tension with Kantianism, Utilitarianism, and pluralism.

2. Would it be possible to create a productive dialogue between Eastern and Western ethical philosophy? What major points of similarity as well as points of difference would you select to focus on for such a discussion? Use the information you’ve learned to construct an answer that will balance both difference and similarity1. Discuss the ways that virtue ethics is in tension with Kantianism, Utilitarianism, and pluralism. In other words, I want you to consider the ways that virtue ethics is compatible with these moral theories, but I also want you to describe ways that it is contrary to these theories. Should we still think of ethics as a matter of virtue or not?

describe the overall concepts of homeland security and homeland defense.

Assignment InstructionsDrawing upon resource material (U.S. National Security Strategies and policies) and that discovered while conducting your own research, students are to develop a research paper of at least 5 full pages (not including title page and reference list) to provide scholarly responses on the following two topics (both must be addressed): Topic 1: Fully describe the overall concepts of homeland security and homeland defense. Construct a response that provides the following related to both homeland security and homeland defense:· Primary missions, tasks, responsibilities, operations, etc. for:o Homeland Security ando Homeland Defense. · Highlight those areas that are shared between the two (what overlaps between HLS and HLD?)· Lastly, recommend a definition for homeland security.Topic 2: Using the overarching themes of the National Security Strategy from 2017, provide your own recommendation for new National Strategy for Counterterrorism (it must be nested under the NSS according to the principle of strategic hierarchy). What key elements and focus areas would you suggest for the part of a new CT strategy that is domestic focused (homeland security, not overseas), and make sure to use the Ends, Ways, and Means strategy framework. Note: Your 5 page paper should be constructed with 1/2 a page for introducing your research paper and your combined thesis, spend 2 whole pages on each of the two above topics, then 1/2 page at the end for your conclusions.· Note: You should be aware of the fact that “homeland security” is made up of much more than just DHS. That agency is only one part of a larger Homeland Security Enterprise that includes [DHS] Departmental leaders and components [the 7 field agencies including USCG, CBP, ICE, USSS, etc], state, local, tribal, territorial and private sector partners and other… https://www.dhs.gov/strengthening-homeland-security-enterprise. Also remember there are many other essential federal agencies that play a role in HLS, such as the very important DOJ where the FBI is the lead agency for countering terrorism in the US (not DHS).Make sure you read the instructions carefully and that you focus your paper on answering the assigned questions. This assignment is a research paper, not an opinion paper, so you need to use scholarly sources to support your thesis. Use formal academic writing and do not use the first person such as ‘I’ or ‘my’; see the OWL site on academic writing style (using appropriate language). Make sure you use APA style in-text parenthetical citations at the end of every sentence where you are quoting another’s ideas (or any information) that is not your own thoughts and words, like this (Bergen, 2015, para 14). Citations are required for paraphrases as well, but not the page or paragraph number in that case. I highly recommend you use the APUS writing guide which can be found in the university library or at this link: APUS Style Guide for APA. You are welcome to use supplementary sources to compliment the assigned readings based upon your research, but make sure you use only scholarly and credible sources (do not use open websites and you never want to use Wikipedia for a college level paper). Also, dictionaries and encyclopedias as well as general news sites (like CNN) are not appropriate for college level research papers. A good example of what NOT to use is NSA.Gov1.info (which some students have tried to use in research papers), not only is it not the NSA webpage, the site loaded with bogus information and if you scroll down to the bottom it says “This is a parody of nsa.gov and has not been approved, endorsed, or authorized by the National Security Agency or by any other U.S. Government agency.” Also, do not cite the weekly lessons as those are only basic information to start off the topic with. You need to use mainly scholarly and reputable academic books and journal articles.Requirements:– Written according to the APA style and format (parenthetical in-text citation formats only; not end notes or footnotes);– Use Times New Roman 12 point font;– 1 inch margins on all sides with no paragraph indentation other than the first line by .5 inches – Double space all text (no extra lines or spaces after a paragraph or section headings and no added font sizes or lines either) – A respectable number of credible resources used, cited in the paper as in-text citations, and included on the reference page. A good rule of thumb is at least 2 scholarly sourcesper page of content (a minimum of 2 new scholarly sources per page in a research paper is acceptable). Use those academic and credible sources provided to you throughout the course, as well as other scholarly material obtained from conducting your own research. Freely utilize appropriate and reputable academic sources, summarize in your own words (paraphrase) and cite accordingly.– The paper must be free of typographical, spelling and grammatical errors (make sure to proof read before submission)– Turn your paper in as a Word Document and title your assignment Finally, be mindful of excessive direct quotes as the paper should not contain just a string of quotations from sources. “Quotes cannot make up more than 10% of the text of your assignment.” So paraphrase where you can and provide your own analysis and synthesis of your research (use direct quotes only when necessary to support your thesis). The bottom line for academic integrity is to write an original work for this assignment (not copied from anywhere on the internet or recycled content from your own previous papers) and to properly cite your references. See the syllabus tab within this course for more important information on academic integrity and the repercussions of plagiarism. Turnitin plagiarism checking software will be used on all papers (automatically).

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