What does the story tell us about strategy, planning and success?
Karl Weick (strategy scholar): “Definitions notwithstanding, I can best show what I think strategy is by describing an incident that happened during military maneuvers in Switzerland. The young lieutenant of a small Hungarian detachment in the Alps sent a reconnaissance unit into the icy wilderness. It began to snow immediately, snowed for two days, and the unit did not return. The lieutenant suffered, fearing that he had dispatched his own people to death. But the third day the unit came back. Where had they been? How had they made their way? Yes, they said, we considered ourselves lost and waited for the end. And then one of us found a map in his pocket. That calmed us down. We pitched camp, lasted out the snowstorm, and then with the map we discovered our bearings. And here we are. The lieutenant borrowed this remarkable map and had a good look at it. He discovered to his astonishment that it was not a map of the Alps, but a map of the Pyrenees.” From: Weick, K. E. (1987) ‘Substitutes for strategy,’ in D. J. Teece (ed.) The Competitive challenge: strategies for industrial innovation and renewal. Cambridge, MA: Ballinger, 222-233.
Q: What does the story tell us about strategy, planning and success?
Give examples of types of innovation for your company at the component and system levels.
Overview
You work as a middle manager for one of the top U.S. producers of luxury and mass-market automobiles and trucks. In response to a VUCA (volatile, uncertain, complex, and ambiguous) world, innovation has become a necessity for most organizations that want to compete in the marketplace. This includes automobile and truck manufacturers. The organization from the course scenario has decided to add IoT technology to its vehicles. While the organization is debating whether to utilize incremental or discontinuous innovation, you have been asked to create a presentation analyzing the dimensions of innovation for your team members. This presentation will help your team members understand the potential options for the organization and the possible technological trajectory (path).
Prompt
Using the information in the overview above and reviewing dimensions of innovation and the five major technological trajectories from your textbook, write a paragraph about the questions below analyzing innovations. It may be helpful to review the CTO Brief, Comparative Growth Data, Comparative Operating Statistics, and Comparative Product Plans documents. Your presentation should include the following points:
1. Give examples of types of innovation for your company at the component and system levels.
2. Describe the potential incremental innovations from the types of innovation and explain why they are incremental.
3. Describe the potential discontinuous innovations from the types of innovation and explain why they are discontinuous.
4. Explain the potential path for your organization by identifying one of the five technological trajectories for your organization along with your justification for that choice.
What are the major barriers preventing Asian populations from seeking mental health services?
Research Question
This project aims to answer the following research question: What are the major barriers
preventing Asian populations from seeking mental health services?
Significance of the Study
According to data and findings collected from the Substance Abuse and Mental Health Services Administration (SAMHSA), the Social Security Administration, and the National Comorbidity Survey – Replication (NCS-R), the National Institute of Mental Health (NIMH) estimates an excess of $300 billion of total annual expenses are related to serious mental illness
which affects about 6% of the adult population. Furthermore, the approximate total amount spent on all items associated with mental illness is rooted from the direct expenditures (e.g., treatment, mental health services), as well as indirect expenditures consisting of losses resulting from disability related to the mental condition (e.g., lost earnings, disability support) (NIMH, 2016).
Lost earnings alone for serious mental illness costs the U.S. about $193.2 billion per year (Insel, 2008). The objectives of this systematic literature review are to analyze a collection of numerous studies published in the past 11 years, identifying barriers hindering Asian populations in the U.S. and Canada from receiving mental health care services and to highlight the trending barriers
found among individual Asian subgroups.
Assumptions
The systematic literature review was conducted by a single author; therefore, the assumption is that the validity of the results may be affected as there is a risk of bias during the assessment of studies. It is further assumed that production of generalize results can be found as majority of the research studies involved quantitative methodology involving large populations.
Lastly, the review can be replicated as it follows a step-by-step systematic process of collecting, examining, and synthesizing data from research studies.
Limitations
The review consisted exclusively of peer-reviewed articles published within an 11-year timeframe. Credible online resources and books were not included as they posed potential complications with coding and issues with data analysis. Due to these limitations, the review may have not examined all pertinent articles. Although, there is certainty that the results may not have differed significantly if there were more articles included. The majority of the studies were conducted in the U.S. and a few from Canada. The review itself uncovered commonalities in barriers to mental health services (e.g., stigma, strong cultural adherence among older immigrants) between both Asian Americans and Asian Canadians which contributed more knowledge of the Asian subgroups found in developed countries. Unfortunately, it does not
reflect all barriers found in populations located in other developed nations within North America.
In addition, bias may have occurred during the article selection process (e.g., setting of inclusion and exclusion criteria) and the reviewing stages (e.g., coding) due to the examination being conducted by one author
What genes are linked to Parkinson’s Disease and what are the environmental factors that effect the development of the disease?
CAPSTONE PROJECT TOPIC
Sibel Uzun
Summary
Parkinson’s Disease ailment is a neurological disorder that is characterized by tremor, slow movement, stiffness of arms and legs, and shaking arms, it is the most common neurodegenerative disease after Alzheimer’s. Research shows that three out of a thousand people aged above 50 years have the condition (Westenberger 2012).
Research Questions (Condense the 4 questions to 2 and then try to condense to 1 question.)
1. What genes are linked to Parkinson’s Disease and what are the environmental factors that effect the development of the disease?
2. Can gene mapping be used in the early diagnosis & treatment of Parkinson’s Disease? Condense to one question.
3. How accurate the results of genetic mapping will be?
4. Will genetic mapping answer the cause ( genetic/environmental) of the gene mutation and development of the disease? Condense to one question.
Study Variables The study variables should be bullet-points or a short list of independent and dependent variables you’ll be assessing.
The study indicated that about 10- 15% of people with Parkinson’s ailment have a family history of the disease. Family-linked cases are a result of genetic mutations in the gene category that includes; SNAC gene, it is responsible for making alpha-synuclein protein, in the brain of a patient with Parkinson’s ailment, this protein gather and form a clump called Lewy bodies. SNCA gene mutation transpires in early Parkinson’s disease. PARK2 gene that helps in making parkin protein that assists in breaking down of cells and protein recycling. PARK7 gene mutation may result in the formation of early Parkinson’s disease, it is responsible for making DJ-1 protein which protects mitochondria from stress. PINK1 protein makes kinase protein that also helps protect mitochondria’s inner structure from stress. PINK1 also occurs in the early stage of Parkinson’s disease. In the inherited instance of Parkston’s, the pattern of inheritance varies, this is because it depends on the involved gene (Lill 2016)
When SNAC and LRRK2 genes are involved, the likeliness of the inherited Parkinson’s is just from a single parent. This is known as an autosomal dominant pattern; this means that only a single gene is required for alteration of the gene hence disorder. If PINK1, PARK2, or PARK7 gene is involved, this state is known as autosomal recessive pattern. This is when two copies of the gene are required to alter for the disorder to be realized meaning that both parents are responsible for the passing of the altered gene but had no sign of the Parkinson’s ailment themselves (Schulzer 2004). Nonetheless, the interlinkage between mutations or generic changes and risk of individual developing the disorder has not been realized fully, the above gene mapping research assist in managing Parkinson’s disease. This is by gene editing, gene transfer, and transplant of stem cells-derived dopaminergic neuron (Duvoisin 1996).
Extensive research has also revealed that Parkinson’s disease can be caused by environmental and genetic factors. Interaction of environment can be complex; some environments lower the risk of Parkinson’s while other increase. Comparably, generic (genetic?) makeup in some people makes them vulnerable to toxic materials than others. Research reveals that a combination of the two factors may enhance biological changes resulting in Parkinson’s (Gasser 2001)
The environmental risk includes; a head injury that may alter the level of consciousness, traumatic head injury has been linked to the risk of developing Parkinson’s ailment however, the underlying mechanism is not clear. Polychlorinated Biphenyls has also been linked to the development of Parkinson’s; many industries use Trichloroethylene as a solvent yet it is known to be a common contaminant of groundwater, exposed to the mentioned chemical is connected to Parkinson’s disease. Also, herbicides and pesticides have been linked to Parkinson’s, one herbicide associated with Parkinson’s is Paraquat that was commonly used in the United States but was banned after the realization of its effect. Study shows that potential environmental causes of Parkinson’s can be managed by; consumption of caffeine in the coffee, Uric acid that occurs naturally in the blood and is associated with diets, taking anti-inflammatory drugs, and regular physical exercise (Logroscino 2005).
Study Design
Systematic literature review. Review the “Young student’s guide to performing a systematic review” in the Ancillary folder.
Instrumentation
Information on the paper has been collected through research from eBooks, scholarly journals, articles from magazines (please avoid infotainment/ads and similar non-peer-reviewed material), and search from the NU library. Be much more specific as to the key published resources and databases from which you’re gathering your information. A systematic review outlines a particular approach.
References (Correct the format for this section.)
I counted six (6) citations in your text but see many more listed here.
Polymeropoulos, M. H., Higgins, J. J., Golbe, L. I., Johnson, W. G., Ide, S. E., Di Iorio, G., … & Duvoisin, R. C. (1996). Mapping of a gene for Parkinson’s disease to chromosome 4q21-q23. Science, 274(5290), 1197-1199.
Klein, C., & Westenberger, A. (2012). Genetics of Parkinson’s disease. Cold Spring Harbor perspectives in medicine, 2(1), a008888.
Gasser, T. (2001). Genetics of Parkinson’s disease. Journal of neurology, 248(10), 833-840.
Lill, C. M. (2016). Genetics of Parkinson’s disease. Molecular and cellular probes, 30(6), 386-396.
Gasser, T. (2007). Update on the genetics of Parkinson’s disease. Movement disorders: official journal of the Movement Disorder Society, 22(S17), S343-S350.
Gasser, T. (1998). Genetics of Parkinson’s disease. Clinical genetics, 54(4), 259-265.
Siderowf, A., & Stern, M. (2003). Update on Parkinson disease. Annals of internal medicine, 138(8), 651-658.
Kumar, A., Calne, S. M., Schulzer, M., Mak, E., Wszolek, Z., Van Netten, C., … & Calne, D. B. (2004). Clustering of Parkinson disease: shared cause or coincidence?. Archives of neurology, 61(7), 1057-1060.
Logroscino, G. (2005). The role of early life environmental risk factors in Parkinson disease: what is the evidence?. Environmental health perspectives, 113(9), 1234-1238.
Warner, T. T., & Schapira, A. H. (2003). Genetic and environmental factors in the cause of Parkinson’s disease. Annals of Neurology: Official Journal of the American Neurological Association and the Child Neurology Society, 53(S3), S16-S25.
Willemsen, M. D., Grimbergen, Y. A., Slabbekoorn, M., & Bloem, B. R. (2000). Falling in Parkinson disease: more often due to postural instability than to environmental factors. Nederlands Tijdschrift voor Geneeskunde, 144(48), 2309-2314.
Koller, W., Vetere-Overfield, B., Gray, C., Alexander, C., Chin, T., Dolezal, J., … & Tanner, C. (1990). Environmental risk factors in Parkinson’s disease. Neurology, 40(8), 1218-1218.
Chin-Chan, M., Navarro-Yepes, J., & Quintanilla-Vega, B. (2015). Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases. Frontiers in cellular neuroscience, 9, 124.
de Wit, S., Barker, R. A., Dickinson, A. D., & Cools, R. (2011). Habitual versus goal-directed action control in Parkinson disease. Journal of Cognitive Neuroscience, 23(5), 1218-1229.
Carpenter, M. G., & Bloem, B. R. (2011). Postural control in Parkinson patients: a proprioceptive problem?. Experimental neurology, 227(1), 26-30.
Pelykh, O., Klein, A. M., Bötzel, K., Kosutzka, Z., & Ilmberger, J. (2015). Dynamics of postural control in Parkinson patients with and without symptoms of freezing of gait. Gait & Posture, 42(3), 246-250.
Scott, W. K., Nance, M. A., Watts, R. L., Hubble, J. P., Koller, W. C., Lyons, K., … & Pericak-Vance, M. A. (2001). Complete genomic screen in Parkinson disease: evidence for multiple genes. Jama, 286(18), 2239-2244.
Dumitriu, A. (2012). Genome-wide expression and genomic data integration analyses in sporadic Parkinsons disease. Boston University.
Maraganore, D. M., De Andrade, M., Lesnick, T. G., Strain, K. J., Farrer, M. J., Rocca, W. A., … & Ballinger, D. G. (2005). High-resolution whole-genome association study of Parkinson disease. The American Journal of Human Genetics, 77(5), 685-693.
Pankratz, N., Nichols, W. C., Uniacke, S. K., Halter, C., Rudolph, A., Shults, C., … & Parkinson Study Group. (2002). Genome screen to identify susceptibility genes for Parkinson disease in a sample without parkin mutations. The American Journal of Human Genetics, 71(1), 124-135.
Ahmed, S. S., Santosh, W., Kumar, S., & Christlet, H. T. T. (2009). Metabolic profiling of Parkinson’s disease: evidence of biomarker from gene expression analysis and rapid neural network detection. Journal of biomedical science, 16(1), 1-12.
You’re starting out well. Consider the focus of your research proposal. Review my comments and suggested revisions.
Where is your Selection of Project Topic? Please complete and submit it, as this is the document I must approve before you move on to Assignment #1.
Medical Law and covid19 situation in England (NHS), “The COVID-19 pandemic has been a crucial turning point for healthcare in England”. Critically analyse this statement in the light of the legal and ethical issues that have arisen or have been heightened by the virus outbreak.
Question –
“The COVID-19 pandemic has been a crucial turning point for healthcare in
England”. Critically analyse this statement in the light of the legal and ethical
issues that have arisen or have been heightened by the virus outbreak. To
support your answer you should use relevant examples that include and go
beyond healthcare rationing issues.
My topic is related to the field of medical law in England .
Question – “The COVID-19 pandemic has been a crucial turning point for healthcare in England”. Critically analyse this statement in the light of the legal and ethical issues that have arisen or have been heightened by the virus outbreak.
To support your answer you should use relevant examples that include and go beyond healthcare rationing issues.
- Font 12 Arial –
- Coursework MUST include a bibliography.
- OSCOLA citation + footnotes at the bottom of the page
- Margins must be a minimum of 2.5cm
- Line spacing must be 1.5.
Resources for this paper
- Germain S. (2020) “Will COVID-19 Mark the End of an Egalitarian National Health Service?” (2020) 11 European Journal of Risk Regulation, 358; and
- Germain S. & Yong A. “COVID-19 Highlighting Inequalities in Access to Healthcare in England: A Case Study of Ethnic Minority and Migrant Women” (2020) Feminist Legal Studies, 301.
- Resource allocation & health care rationing issues are key subjects of this paper
Textbooks to use – One of these is fine , preferably Jackson
- Emily Jackson chp 2- Texts /cases/materials 5th edition
- Mason & McCall Smith chp 2 & 11; or
- Pattinson chp 2;
Additional resources :
- British Medical Association (2020) “COVID-19-Ethical Issues. A Guidance Note”.
- Royal College of Physicians (2020) “Ethical Dimensions of COVID-19 for Frontline Staff”.
Was this a violation of Peter’s Sixth Amendment right to counsel?
What is assistance of counsel?
For example: Two college friends, Richard and Peter are arrested by the Capital City police. They are accused of murder for setting fire to the Capital City University administration building one night and causing the death of a janitor in the fire. Both Richard and Peter were members of a student organization that claimed that the administration of the University was corrupt, and at a rally they carried signs outside the building that read “Burn it to the ground.”
Richard’s father is very rich. He hires a team of the most expensive lawyers in the country, and after an eight-day trial, Richard is acquitted by a jury. Richard’s lawyers sought and received a separate trial for him.
Peter’s parents have no money, and Peter has massive student loans and works two jobs to pay for school. He is represented by a public defender who has 120 other cases. Though the public defender does his best with limited time and resources, Peter is convicted after a three-day jury trial.
Peter is now appealing his conviction, claiming that having a public defender with 120 cases effectively denied his right to counsel.
Was this a violation of Peter’s Sixth Amendment right to counsel? Fully explain your answer. Be sure to support your answer with scholarly sources and appellate court opinions.
Critically address the next social, cultural, ethical or environmental shift and its impact on the global fashion culture.
Fashion can be ephemeral or it can be profound
“A 2500-word critical essay showing a coherent and comprehensive understanding of a range of sociological and anthropological theories and their application to the analysis of fashion and culture. Students will critically address the next social, cultural, ethical or environmental shift and its impact on the global fashion culture. Fashion can be ephemeral or it can be profound. Through referencing existing structures compose a critical essay that addresses fashion’s cultural position as an instigator of social change, artistic endeavour or as an extension of the entertainment industry.
The topic i want to analyze is Hip-hop sub-culture and Dapper dan
o 2,500-word Critical essay
Introduction – approx. 500 words
Body – approx. 1,500 words
Conclusion – approx. 500 words
o Bibliographical Acknowledgements List of References
Bibliography
Which medications on her list may you call into the pharmacy and which would you need a written script or electronic order?
In 600 or fewer words, but a minimum of 250, please describe your approach with this patient. In your paragraphs, include the following:
What concerns do you have about her current regimen, and what alternatives will you discuss and offer? What other screenings might you apply? What are your own ethical standards on this case that you might consider in addition to legal standards?
Provide a sample of an appropriate pain contract that would suit this patient and address her specific safety concerns .
Include your steps to ensure safe prescribing. Include the registry you will search prior to any prescribing; name the CA registry and if you are in a different state, you should name that registry also.
If you were to keep her current list, what are the laws surrounding refills and the amounts you are allowed to dispense with the schedule II and III medications in the state of CA? In your own state?
Which medications on her list may you call into the pharmacy and which would you need a written script or electronic order? What are some elements required to include on the prescription form for the scheduled medications?
After you prescribe, how, when, and where would you go about making a report of your scheduled prescription in the state registry so that other prescribers and pharmacies could be aware?
In restricted states, APRN prescribers must follow a standardized procedure or protocol for furnishing schedule II and III controlled substances with a patient-specific approach. Please outline the minimum required components of a protocol. You may outline this in bullet form. Alternatively, you may find an appropriate protocol, clinical guideline, or standardized procedure from a literature search and attach it in lieu of outlining your own protocol.
Identify the addiction that this client presents with. Does she have a substance addiction like alcohol, prescriptions, or illicit drugs?
2-2 Case Study Milestone One
In this milestone, you will be reading Case Study 3 and writing a short paper based on the following prompt. You will be focusing on the addiction and its effects. Consider the following in your short paper:
Case Study 3 Website
Client information and presenting problem
Identify the client.
Identify the addiction that this client presents with.
Does she have a substance addiction like alcohol, prescriptions, or illicit drugs?
Does she have a process addiction like gambling, video gaming, or shopping?
Provide the history of the addiction.
What is the history of the addiction? Remember, there are many types of addiction, and not all were defined around that time. For example, video game addiction was not officially defined until 1995, while alcohol addiction was defined in 1941.
What is the impact of her addiction on herself, her family, her community, and/or society?
What are the consequences for her, her family, her workplace, and her community due to the addiction?
Has she lost her family, job, friends, community standing, self-esteem, credibility, freedom?
Results
Discuss the results of this case.
Did the client respond positively to the treatment?
Did the client relapse?
Your paper should:
Be composed in MS Word and formatted in APA style
Be at least 3 pages in length, not including the title page and references page
Employ a minimum of two scholarly sources
For additional details, please refer to the Case Study Milestone One Guidelines and Rubric document.
Discuss the nursing management, including teaching needs for a patient with diabetes.
Be sure to completely answer all the questions / topics listed below. There should also be an introduction which briefly discusses the topic and a conclusion. Separate each section in your paper with a clear heading that allows your professor to know which topic you are addressing in that section of your paper. Support your ideas with at least three (3) sources in your essay. Make sure to reference the citations using the APA writing style for the essay. The cover page and reference page do not count towards the minimum word amount. Review the rubric criteria for this assignment.
Compare and contrast between diabetes mellitus Type 1 and 2. Describe the clinical manifestations, pathophysiology, and diagnostic studies of diabetes.
Explain the interprofessional care of diabetes: include prevention, and medication. Discuss the nursing management, including teaching needs for a patient with diabetes.
Discuss the acute and chronic complications of diabetes. Structure: Include a title page and reference page in APA style. These do not count towards the minimal word amount for this assignment.
