How did science and technology shape American history from the pre-colonial period through the 1860s?

How did science and technology shape American history from the pre-colonial period through the 1860s? Please select three words that you think best capture their impact on the history we studied over the course of the semester. Examples of words you might choose include: progress, expansion, innovation, health, power, transformation, inequality, suffering, destruction, complexity, paradox, unintended consequences.
The structure of your essay is as follows:

Paragraph #1: Introduction and discussion of your thesis/argument

Paragraph #2: Word #1 drawing upon discussion of specific historical examples/evidence from course material

Paragraph #3: Word #2 drawing upon discussion of specific historical examples/evidence from course material

Paragraph #4: Word #3 drawing upon discussion of specific historical examples/evidence from course material

Paragraph #5: Conclusion reiterating main argument and its implications