Infection Science, Discuss the innate and adaptive immunological responses to the M. tuberculosis infection.

Biology

Section A 1. 1000 words. 10 references Harvard.

A patient who lived in China for 2 years presented himself to his GP with a lack of appetite, weight loss, night sweats, high fever, extreme tiredness and fatigue. He had breathlessness and a persistent cough for 6 months with bloody phlegm. A chest X-ray revealed minimal changes to his lungs. A sputum test detected the presence of Mycobacterium tuberculosis suggesting that he had active tuberculosis.
(a) Explain the mode of transmission of the bacterium. (5 marks) 100 words min
(b) Discuss the cells targeted by the bacterium and the mechanism of their infection. (10 marks) 300 words min
(c) Discuss the innate and adaptive immunological responses to the M. tuberculosis infection. (30 marks) 400-500 words min
(d) Discuss the progression and the outcome of the disease if left untreated. (5 marks) 100 words min

in total 1000 words min